Due to hazards of addiction, abuse, and misuse with opioids, even at recommended doses [see Warnings and Safeguards (five.1)], reserve Promethazine HCl and Codeine Phosphate Oral Alternative to be used in Grownup sufferers for whom the benefits of cough suppression are predicted to outweigh the threats, and in whom an adequate assessment of the etiology from the cough continues to be designed.
Although it can help many people, this medication provides a chance for abuse and could occasionally cause addiction. This threat could be bigger For those who have a substance use condition (which include overuse of or dependancy to prescription drugs/alcohol).
Promethazine Symptoms and indications of overdosage with promethazine range between moderate melancholy of the central nervous technique and cardiovascular method to profound hypotension, respiratory despair, unconsciousness and sudden death.
To assist stop withdrawal, your physician may perhaps decrease your dose little by little. Withdrawal is a lot more probably For those who have utilized this medication for years (more than a few months) or in high doses. Explain to your health care provider or pharmacist instantly if you have withdrawal.
The urge to cough occurs within your brain, especially the brainstem. Opioids like codeine block this urge by Functioning onmu and kappa opioid receptorsin the brainstem.
are Expecting or program to be Expecting. Promethazine Hydrochloride and Codeine Phosphate Oral Solution can damage your unborn toddler. See “Precisely what is The most crucial information I really should know about Promethazine Hydrochloride and Codeine Phosphate Oral Answer?” are breastfeeding or want to breastfeed. Codeine passes into your breast here milk and may cause major Negative effects as part of your infant like enhanced sleepiness, respiration complications (respiratory despair), and death. It isn't identified if promethazine can pass into your breast milk.
Like more info other codeine merchandise, codeine linctus is usually habit-forming and can result in addiction or overdose.
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Bone marrow suppression can lead to infections or bleeding. This can be really serious or even existence-threatening. Continue to keep all appointments to have your blood checked. Inform your healthcare company at click here once When you have any of the next signs or symptoms of bone marrow suppression.
This medication could interfere with certain clinical/lab exams (which include amylase/lipase stages, allergy pores and skin examination, Mind scan for Parkinson's illness), quite possibly leading to Phony examination effects. Make certain lab staff and your Health professionals know you use this drug.
INDICATIONS AND Use Promethazine HCl and Codeine Phosphate Oral Remedy is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for your non permanent relief of cough and higher respiratory indicators affiliated with allergy or the widespread cold in individuals 18 years of age and older. (1)
Convey to click here your doctor If you're Expecting or Feel you may well be Expecting. All through pregnancy, this item just isn't advisable. It may hurt an unborn toddler. Discuss with your medical professional about the risks and great things about this medication. See also Warning area.
Drug habit is usually a cluster of behavioral, cognitive, and physiological phenomena that produce following recurring compound use and consists of: a solid want to take the drug, difficulties in controlling its use, persisting in its use despite harmful implications, the next precedence supplied to drug use than to other actions and obligations, amplified tolerance, and often a Actual physical withdrawal.
長期使用時，身體可對可待因產生耐藥性，令藥效減弱，並有可能產生依賴性。